Key facts about the registry
Publications of the past years have demonstrated that many patients with chronic urticaria and urticarial vasculitis experience a major impairment of their health-related quality of life. In addition, a considerable proportion of patients experience these conditions for years or life-long.
Despite the high prevalence of chronic urticaria and the availability of some retrospective data on its progression, key aspects such as its epidemiology, comorbidities, disease duration, underlying causes, treatment responses, and associated medical costs remain insufficiently studied. While urticarial vasculitis (UV) is less common, it often results in more severe symptoms and a greater reduction in quality of life compared to chronic spontaneous urticaria (CSU). UV frequently presents with systemic symptoms such as joint pain, fever, and fatigue, which are less typical in CSU, further intensifying its impact on patients’ daily lives. To address these gaps in understanding and improve care, a registry is a crucial tool for capturing real-life data on both conditions.
Collaborative
Framework
- Investigator-initiated registry coordinated by non profit limited liability company UNEV gGmbH
- Academia-driven – UCAREs and other physicians / sites who treat patients with chronic urticaria
- Endorsed by national and international scientific and medical societies
- Cooperation with stakeholders (industry, patient organizations, payers, health authorities)
- Open to all urticaria-treating physicians / centers
- Open to all chronic urticaria patients
Key features of CURE
Web-based-registry
Access and manage your important records effortlessly with our user-friendly web-based registry.
Effortless Data Entry for Physicians
Patient module (entered once in 30 minutes) and Physician module (entered once in 7 minutes).
Simple Follow-up Data Entry for Physicians
Patient module (entered every 6 months in 15 minutes).
Inclusive Participation
Registry population
CURE is open to all chronic urticaria and urticaria vasculitis-treating physicians/sites. It is the intention of CURE to obtain data from as many patients as possible. There is no predefined sample size as this is an observational registry. There is also no limit with regard to the age or gender of patients. No selection of patients is intended since it is the aim to collect unbiased data from the real life clinical setting.
Advancements in the Exploration
Data Analyses, Interpretation and Publications
CURE aims to improve the knowledge on chronic urticaria and urticaria vasculitis, by CURE data analyses, interpretation, reporting and publication. Reports containing descriptive information as well as the results of analyses of CURE patient data will be provided for information to CURE ISC members, CURE investigators and eligible partners at regular intervals. In addition to these regular descriptive data summaries, specific analyses of scientific or clinical interest are conducted.
79 centers in 31 countries
Distribution of participating centers
Number of datasets
